Managing Premature Ejaculation: How POXET-60 Improves Control and Satisfaction

POXET-60是一种专门用于治疗早泄的口服药物，其活性成分为盐酸达泊西汀，属于选择性5-羟色胺再摄取抑制剂。它通过调节大脑中的神经递质来帮助延长射精时间。POXET-60通常为灰色薄膜衣片，常见规格为60毫克/片，需在医生指导下按需服用。

POXET-60 is an oral medication specifically used for the treatment of premature ejaculation. Its active ingredient is Dapoxetine Hydrochloride, which belongs to the class of selective serotonin reuptake inhibitors. It works by regulating neurotransmitters in the brain to help delay ejaculation. POXET-60 is typically a gray film-coated tablet, commonly available in 60mg strength, and should be used as needed under medical supervision.

Click to buy

2. 作用机制 / Mechanism of Action

POXET-60通过抑制神经元对5-羟色胺的再摄取，增加突触间隙的5-羟色胺浓度，从而增强射精控制能力。这种作用有助于延长射精潜伏期，改善性生活质量。药物口服后约1-2小时达到血药浓度峰值，建议在性活动前1-3小时服用。

POXET-60 works by inhibiting the reuptake of serotonin by neurons, increasing serotonin concentration in the synaptic cleft, thereby enhancing ejaculatory control. This action helps to prolong the ejaculation latency and improve sexual quality. The drug reaches peak plasma concentration approximately 1-2 hours after oral administration, and it is recommended to be taken 1-3 hours before sexual activity.

3. 用法用量 / Usage and Dosage

用法：整片吞服，足量水送服（建议至少350毫升），不可咀嚼。
Administration: Swallow the tablet whole with a full glass of water (at least 350ml recommended); do not chew.
剂量：推荐起始剂量为30毫克，可根据疗效和耐受性增至60毫克，24小时内不超过一次。餐前餐后均可服用，但高脂肪食物可能延迟起效。
Dosage: The recommended starting dose is 30mg, which may be increased to 60mg based on efficacy and tolerance, not exceeding once per 24 hours. It can be taken with or without food, but high-fat meals may delay its effect.
疗程：需在用药后4周或6次剂量后评估效果，由医生决定是否继续使用。
Course: Efficacy should be evaluated after 4 weeks or 6 doses, and a doctor should decide whether to continue treatment.

4. 适用人群与禁忌 / Target Audience and Contraindications

适用人群：18-64岁早泄男性，无严重心、肝、肾功能问题。
Target Audience: Men aged 18-64 with premature ejaculation, without severe cardiac, hepatic, or renal impairment.
禁忌：对成分过敏者；严重心脏病患者；正服用单胺氧化酶抑制剂、强CYP3A4抑制剂（如酮康唑）或特定精神药物者；中重度肝损伤患者。
Contraindications: Hypersensitivity to ingredients; patients with severe heart conditions; those taking MAOIs, strong CYP3A4 inhibitors (e.g., ketoconazole), or certain psychiatric drugs; patients with moderate to severe liver impairment.

5. 潜在副作用 / Potential Side Effects

常见副作用包括头痛、眩晕、恶心、腹泻、失眠和疲劳，通常较轻微。严重副作用罕见，可能包括晕厥（常伴前驱症状如头晕）或直立性低血压。若出现严重反应（如心悸、晕厥），需立即就医。

Common side effects include headache, dizziness, nausea, diarrhea, insomnia, and fatigue, which are usually mild. Serious side effects are rare but may include syncope (often with precursors like dizziness) or orthostatic hypotension. Immediate medical attention is required if severe reactions (e.g., palpitations, syncope) occur.

6. 注意事项 / Precautions

药物相互作用：避免与酒精、硝酸酯类药物、CNS抑制剂或兴奋剂同用，以防加重副作用。
Drug Interactions: Avoid concurrent use with alcohol, nitrates, CNS depressants, or stimulants to prevent aggravated side effects.
特殊人群：老年人、轻中度肾损伤者慎用；重度肾损伤、中重度肝损伤者禁用。
Special Populations: Use with caution in the elderly and those with mild to moderate renal impairment; contraindicated in severe renal impairment and moderate to severe hepatic impairment.
存储：常温保存，避光防潮，置于儿童不可及处，有效期通常为36个月。
Storage: Store at room temperature, protected from light and moisture, keep out of reach of children, shelf life is typically 36 months.

7. 常见问题解答 / Frequently Asked Questions (FAQs)

Q1: POXET-60是否可每日服用？
A1: 否，它仅为按需服用，24小时内勿超一次。

Q1: Can POXET-60 be taken daily?

A1: No, it is only for on-demand use; do not exceed once per 24 hours.
Q2: 停药后是否有戒断反应？
A2: 长期使用后突然停药可能引发焦虑、失眠等，需在医生指导下逐渐减量。

Q2: Are there withdrawal symptoms after discontinuation?

A2: Sudden cessation after long-term use may cause anxiety, insomnia, etc.; taper off under medical guidance.
Q3: 如何评估疗效？
A3: 可通过射精潜伏期延长和患者满意度综合评估，建议定期复诊。

Q3: How to evaluate efficacy?

A3: Assess via prolonged ejaculation latency and patient satisfaction; regular follow-ups are recommended.